Finding

What does this study add?

• After 6 months, all three groups showed improvement across clinical measures, with good initial increases in quality of life.
• However, laser-only patients did not maintain their quality of life improvements over time.
• Results from Groups 2 and 3 suggest that metformin and combined oral contraceptives both affect the underlying mechanism of the disease.
• Patients in the contraceptive group showed the biggest overall improvement in quality of life, and this continued to increase out to 6 months.