Digestive Diseases
| Ulcerative colitis
Digestive Diseases
Ulcerative colitis

VEGA: Early local colonic tissue healing with guselkumab maintenance after induction with guselkumab and golimumab combination

book_2 Source: ECCO 2024 - Oral session 
calendar_today Published on Medfyle: March 2024
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Guselkumab and golimumab are biologic therapies with different mechanisms of action. A substudy of the VEGA trial was designed to explore early molecular changes in a subset of patients. The results help to define the mechanistic contributions of each drug in monotherapy, and as combination.

Expert commentary

Laurent Peyrin-Biroulet, MD, PhD

Nancy University Hospital
Nancy, France

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Source: Richards D, Vetter M, Germinaro M, et al. DOP54 Tofacitinib for hospitalized acute severe Ulcerative Colitis – the TRIUMPH study. J Crohns Colitis 2024;18(suppl1):jjad212.0094 [DOP54]

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The author(s) of the original article had no involvement in the creation of this content.


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