Role of PAR-2 Receptors in Migraine Using a Novel, Translatable Injury-Free Preclinical Model
In this medfyle
Expert commentary by Andrew Russo, PhD
This Medfyle was published more than two years ago. More recent Medfyle on this topic may now be available.
Acknowledgements
This is a highlights summary of an oral session given at the AHSAM 2020 Virtual Annual Scientific Meeting and presented by:
Caroline Kopruszinski, PhD
Postdoctoral researcher
University of Arizona
Tucson, Arizona
The content is produced by Infomedica, the official reporting partner of ASHAM 2020 Virtual Annual Scientific Meeting. The summary text was drafted by Goldcrest Medical Writing, reviewed by Marco Vercellino, MD, an independent external expert, and approved by Jessica Ailani, MD, FAHS and Mark J. Burish, MD, PhD, the scientific editors of the program.
The presenting authors of the original session had no part in the creation of this conference highlights summary.
In addition, an expert commentary on the topic has been provided by:
Andrew Russo, PhD
University of Iowa, Iowa City, IA, USA
About the Expert
Andrew Russo, PhD
University of Iowa, Iowa City, IA, USA
Andrew Russo is Professor of Molecular Physiology and Biophysics, and Neurology, at the University of Iowa. Dr. Russo received his PhD in Biochemistry from the University of California, Berkeley, followed by postdoctoral training in molecular neurobiology at UCSD. Dr. Russo’s research is focused on how the neuropeptide CGRP contributes to the altered sensory perception and pain of migraine. The lab uses approaches ranging from epigenetics to mouse behavior. The overall goal of his studies is to develop effective diagnostic and therapeutic strategies for migraine and post-traumatic headache.
References
1. Nassini R, Materazzi S, Vriens J, et al. The ‘headache tree’ via umbellulone and TRPA1 activates the trigeminovascular system, Brain 2012;135:376–390.
2. Benemei S, Appendino G, Geppetti P. Pleasant natural scent with unpleasant effects: cluster headache-like attacks triggered by Umbellularia californica. Cephalalgia 2010;30:744-746.
