Oncology
| NSCLC immunotherapy combinations
Oncology
NSCLC immunotherapy combinations

Phase II Randomized Study of Ramucirumab and Pembrolizumab Versus Standard of Care in Advanced Non–Small-Cell Lung Cancer Previously Treated With Immunotherapy—Lung-MAP S1800A

book_2 Source: J Clin Oncol. 2022;40(21):2295-2306. 
calendar_today Published on Medfyle: October 2022
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In this medfyle

Ramucirumab plus pembrolizumab led to improved OS compared with standard of care in patients with advanced NSCLC previously treated with chemotherapy and immunotherapy with acquired resistance to prior ICI in this randomized phase II trial.

This Medfyle was published more than two years ago. More recent Medfyle on this topic may now be available.

Expert commentary

Martina Imbimbo, MD

University Hospital of Lausanne, CHUV
Lausanne, Switzerland

About this Medfyle
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This Medfyle is provided as a service to healthcare professionals. It has been created from content originally published in the Journal of Clinical Oncology® (JCO), an American Society of Clinical Oncology Journal, through an official agreement with Wolters Kluwer.

The summary content was prepared by Louise Gardner for Medfyle, reviewed & approved by Dr Martina Imbimbo.

Original article:
Reckamp KL, Redman MW, Dragnev KH, Minichiello K, Villaruz LC, Faller B, Al Baghdadi T, Hines S, Everhart L, Highleyman L, Papadimitrakopoulou V, Gandara DR, Kelly K, Herbst RS. Phase II Randomized Study of Ramucirumab and Pembrolizumab Versus Standard of Care in Advanced Non-Small-Cell Lung Cancer Previously Treated With Immunotherapy-Lung-MAP S1800A. J Clin Oncol. 2022 Jul 20;40(21):2295-2306. doi: 10.1200/JCO.22.00912. Epub 2022 Jun 3. PMID: 35658002.

The authors of the original article had no part in the creation of the summary.

All Medfyle content, summaries, expert commentaries and slides are owned by GlobalPort (International) Limited. The original journal articles are an exclusive copyright of the American Society of Clinical Oncology.


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