- Versteijne E, Suker M, Groothuis K, et al. Preoperative chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: Results of the Dutch randomized phase III PREOPANC trial. J Clin Oncol 2020;38(16):1763-1773.
Long-Term Results of the Dutch Randomized PREOPANC Trial
Key messages
- Long-term overall survival is improved for patients with resectable and borderline resectable pancreatic cancer treated with neoadjuvant gemcitabine-based chemoradiotherapy compared with upfront surgery.
- The beneficial effect of neoadjuvant chemoradiotherapy is consistent across patient subgroups.
- Further studies are warranted to understand the optimal neoadjuvant regimen.
