
Hematology
| MM
Hematology
MM
BCMA- or GPRC5D-targeting bispecific antibodies in multiple myeloma: efficacy, safety, and resistance mechanisms
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Source:
Blood. 2024;143(13):1211-17
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Published on Medfyle:
June 2024
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7
min
In this medfyle
Recent approvals of teclistamab, elranatamab and talquetamab by health authorities highlight the significant efficacy of TCEs in the treatment of MM, particularly for patients with heavily treated relapsed or refractory disease. Despite their promising clinical outcomes, challenges remain in optimizing their use. The effectiveness and safety of these novel agents are reviewed and strategies to enhance their therapeutic potential in MM are explored in a review article.