Diabetes
| Type 2 diabetes
Diabetes
Type 2 diabetes

Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis

book_2 Source: Diabetologia. 2022;65(8):1251-1261.
calendar_today Published on Medfyle: January 2023
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Tirzepatide is a new option in the management of T2D, which offers synergistic effects on beta cells. This systematic review and meta-analysis of published trials to date found tirzepatide to be superior to placebo, long-acting GLP-1RA, and basal insulin in reducing HbA1c and body weight in adults with T2D, regardless of background glucose-lowering therapy.

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Expert commentary

Michael A. Nauck, MD, PhD

Diabetes, Endocrinology, Metabolism Section, Medical Department 1
St. Josef-Hospital Bochum, Germany

About this Medfyle
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This Medfyle is provided as a service to healthcare professionals. It has been created from content originally published in Diabetologia, the Journal of the European Association for the Study of Diabetes (EASD), and is published in collaboration with Spinger Nature (SNCSC). This MedFyle was created by GlobalPort (International) Limited with permission from Springer Nature (SNCSC).

The summary content was prepared by Marie Farrow for Medfyle, reviewed & approved by Michael A. Nauck MD, PhD Bochum, Germany.

Original article:

Karagiannis T, Avgerinos I, Liakos A, Del Prato S, Matthews DR, Tsapas A, Bekiari E. Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis. Diabetologia. 2022 Aug;65(8):1251-1261. doi: 10.1007/s00125-022-05715-4. Epub 2022 May 17. PMID: 35579691; PMCID: PMC9112245.

The authors of the original article had no part in the creation of the summary.

All Medfyle content, summaries, expert commentaries and slides are owned by GlobalPort (International) Limited. The original journal articles are an exclusive copyright of Springer Nature.


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