Glucagon-like peptide-1 receptor agonists and risk of thyroid cancer: A systematic review and meta-analysis of randomized controlled trials
In this medfyle
This meta-analysis confirms a safety signal, suggesting a possible link between GLP-1RA and thyroid cancer. This could be down to expression in thyroid cells, but there are also links between thyroid cancer and obesity and insulin resistance. More studies are needed to investigate the risks and the underlying biology.
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Original article:
Silverii GA, Monami M, Gallo M, Ragni A, Prattichizzo F, Renzelli V, Ceriello A, Mannucci E. Glucagon-like peptide-1 receptor agonists and risk of thyroid cancer: A systematic review and meta-analysis of randomized controlled trials. Diabetes Obes Metab. 2024 Mar;26(3):891-900. doi: 10.1111/dom.15382. Epub 2023 Nov 29. PMID: 38018310.
The authors of the original article had no part in the creation of the summary.
This Medfyle is provided as a service to healthcare professionals. It has been created from content originally published in Diabetes, Obesity and Metabolism, a Journal of pharmacology and therapeutics, by agreement with Wiley.
