
ENVISION Exploratory Analysis: Sibeprenlimab Reduces Circulating Immune Complexes in IgAN
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Deposition of IgA-containing circulating immune complexes in the kidney is a hallmark of IgAN. Exploratory data presented at Kidney Week 2024 show the anti-APRIL antibody sibeprenlimab reduces these complexes, and correlates with reductions in UPCR.
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Source: The Anti-APRIL Antibody Sibeprenlimab Reduces Circulating Immune Complexes in Patients with IgAN: The Phase 2 ENVISION Randomized Controlled Trial. Barratt J, et al. Presented at Kidney Week 2024; #FR-OR59.
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