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- Shepherd M, Shields B, Hammersley S, et al. Systematic population screening, using biomarkers and genetic testing, identifies 2.5% of the U.K. pediatric diabetes population with monogenic diabetes. Diabetes Care 2016;39(11):1879–88.
Perspectives
How does this paper impact clinical practice?
- Where MODY-monogenic diabetes is suspected, a family history going back at least three generations should be obtained.
- Family history features can help distinguish between type 2 diabetes and MODY-monogenic diabetes.
- Genetic identification is important, since treatment is tailored to the specific variant.
