- Cameron FJ, de Beautfort C, Aanstoot HJ, et al. Lessons from the Hvidoere International Study Group on childhood diabetes: be dogmatic about outcome and flexible in approach. Pediatr Diabetes 2013;14(7):473–80.
- Van Locke M, Battelino T, Tittel SR, et al. Lower HbA1c targets are associated with better metabolic control. Eur J Pediatr 2021;180(5):1513–20.
- Prahalad P, Ding VY, Zaharieva DP, et al. Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Type 1 Diabetes: the Pilot 4T Study. J Clin Endocrinol Metab 2022;107(4):998–1008.
Background
What do we already know about this topic?
- The majority of patients with type 1 diabetes (T1D) do not meet their HbA1c targets, which has an impact on outcomes.
- Consistent target setting and tight goals are associated with improved outcomes.1,2
- In the Pilot 4T study (diagnosed July 2018 to May 2020; HbA1c target <7.5%; n=135), early continuous glucose monitoring (CGM) initiation and remote patient monitoring (RPM) was associated with lower HbA1c.3
How was this study conducted?
- It was hypothesized that tightening HbA1c targets to <7% would further lower HbA1c.
- All youth with newly diagnosed T1D from June 2020 to December 2021 were offered CGM initiation in the first month of diagnosis and RPM (4T cohort; n=115).
- HbA1c outcomes were compared between the 4T and Pilot 4T cohort, and with the historical cohort who were not offered early CGM (diagnosed 2014–2016; n=272).
