- Cameron FJ, de Beautfort C, Aanstoot HJ, et al. Lessons from the Hvidoere International Study Group on childhood diabetes: be dogmatic about outcome and flexible in approach. Pediatr Diabetes 2013;14(7):473–80.
- Van Locke M, Battelino T, Tittel SR, et al. Lower HbA1c targets are associated with better metabolic control. Eur J Pediatr 2021;180(5):1513–20.
- Prahalad P, Ding VY, Zaharieva DP, et al. Teamwork, Targets, Technology, and Tight Control in Newly Diagnosed Type 1 Diabetes: the Pilot 4T Study. J Clin Endocrinol Metab 2022;107(4):998–1008.
Perspectives
How does this study impact clinical practice?
- Early CGM initiation and RPM combined with tighter glucose targets was associated with a lower HbA1c compared to historical cohorts.
- There is a need to intensify education to improve early outcomes for youth with T1D.
- These data support implementation of the 4T program with tighter target setting in youth with T1D, but implementation is a team effort.